hrp0086p1-p207 | Diabetes P1 | ESPE2016

Interrelation between ACE Gene I/D Polymorphism and Chronic Kidney Disease Severity in Uzbek Children and Adolescents with Type 1 Diabetes Mellitus

Rakhimova Gulnara , Sadykova Akida

Background: Generally, diabetic nephropathy onsets and progresses within 5–10 years after DM onset resulting in chronic kidney disease (CKD) causing death in every 4–5th patient with type I DM. Molecular-genetic studies of endogenous/genetic CKD risk factors are of high relevance in understanding of pathogenetic mechanisms underlying formation of nephrosclerosis, and in improvement of interventions.Objective and hypotheses: To assess renal func...